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Last Updated: 4 months ago

Possible Interaction: Azathioprine and Glycerol



Research Papers that Mention the Interaction

It appears that HAES, but not glycerol , significantly reduces ATP concentrations whereas both lead to a reduction of 2,3-DPG concentrations; this reduction was more pronounced with glycerol than with HAES.
Vox sanguinis  •  1992  |  View Paper
When 1 mM ATP is added to human dermal fibroblasts (DF) in monolayer culture permeabilized by glycerol , they undergo a rapid reduction in length and their intracellular actin filaments aggregate.
Journal of cellular physiology  •  1986  |  View Paper
Erythrocytes depleted of ATP in the presence of glycerol can have their ATP levels repleted by either pyruvate or inosine, but require the presence of both compounds for maintenance during a post-rejuvenation incubation period.
Vox sanguinis  •  1979  |  View Paper
ATP content was largely unaffected by treatments, with the exception of glycerol which decreased ATP levels.
PeerJ  •  2014  |  View Paper
This would offset loss of the hydrogen bonds at the gamma-phosphate of ATP during phosphoryl transfer to glycerol , suggesting that appropriate alignment of the second substrate of glycerol kinase, the ATP molecule, may largely determine the rate of glycerol 3-phosphate production.
Biochemistry  •  2009  |  View Paper
Experiments using various inhibitors showed that a large amount of ATP was required not only for the synthesis and accumulation of glycerol but also for the exclusion of Na+ and Cl- from cells under salt-stressed conditions.
Microbios  •  1992  |  View Paper
The total intracellular concentration of ATP in strain Lin 8 was reduced by 85% within 30 s after the addition of glycerol.
Journal of bacteriology  •  1978  |  View Paper
In the absence of acetylglutamate, glycerol (an effective activator) reduces the Km's for ATP and K+, increases the Vmax, and dramatically reduces the S0.5 for acetylglutamate to <1 μM for the synthetase reaction.
In the presence of excess acetylglutamate, glycerol markedly reduces the Km for ATP for the synthetase, decreases the Vmax, NH4+ becomes a more effective activator than K+, and Na+ activates appreciably.
Molecular and Cellular Biochemistry  •  1983  |  View Paper
Liver ATP levels were reduced 24% after glycerol injection.
Possible lowering of hepatic ATP levels by the use of glycerol in humans is another concern.
Journal of neurochemistry  •  1981  |  View Paper
Isolated tissue permeabilized with Triton X-100 or glycerol reversibly contracted in the presence of ATP.
The Journal of comparative neurology  •  2003  |  View Paper
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