Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Azathioprine and Edetic Acid


Edetic Acid

Research Papers that Mention the Interaction

Presence of EDTA inhibited conversion of ADP to ATP (prior to luminescence measurement), presumably through a drop in pH caused by the interaction between H 2 EDTA 2− and the Mg 2+ of the pyruvate-kinase system employed.
Analytical biochemistry  •  1972  |  View Paper
The addition of ATP and Mg ++ together enhanced the inhibition of lactic acid production seen with ATP alone, as did the addition of ATP and EDTA together.
The Journal of laboratory and clinical medicine  •  1967  |  View Paper
The D1 cleavage was greatly facilitated by the addition of 0.15 mM ZnCl2 and 1 mM ATP and was completely inhibited by 1 mM EDTA , indicating the participation of an ATP-dependent metalloprotease(s) in the D1 cleavage.
The Journal of biological chemistry  •  2006  |  View Paper
The ability of ATP to protect even under conditions in which enzyme phosphorylation was prevented by EDTA provides evidence for a distinct ATP-induced protein conformation that acts as an intermediate in energy coupling.
Biochemistry  •  1996  |  View Paper
EDTA and inorganic phosphate are strongly inhibitory, while ATP and high concentrations of 2-mercaptoethanol are slightly inhibitory.
European journal of biochemistry  •  1977  |  View Paper
EDTA decreases both grade and rate of the optical change of myosin B caused by ATP addition.
Biochimica et biophysica acta  •  1957  |  View Paper
EDTA potentiated actions of ADP and ATP on endothelial cells by 2.4- and 3.6-fold, respectively.
Molecular pharmacology  •  1998  |  View Paper
A 'stop solution' containing EDTA was prepared, which greatly retarded plasma ATP degradation by chelating Mg(+2) and Ca(+2) that are co-factors for many ATPases.
Luminescence : the journal of biological and chemical luminescence  •  2003  |  View Paper
The V-ATPase inhibitors, suramin, EGTA or EDTA significantly reduced the granular size increase in the presence of ATP.
Receptors & channels  •  1999  |  View Paper
The oxidative inactivation promoted by ATP is inhibited by Mg2+, Mn2+, catalase, and EDTA , is not mediated by dehydroascorbate, and is not associated with oxidation of cysteines 1327 and 1337.
The Journal of biological chemistry  •  1992  |  View Paper
Show More