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Last Updated: 2 years ago

Possible Interaction: Atropine and Procaine

supplement:

Procaine

Research Papers that Mention the Interaction

In the dog, atropine 0.6 microgram/ml inhibited the former while procaine 400 micrograms/ml stimulated the latter.
Urology  •  1984  |  View Paper
Moreover it reverses inhibitions of the electrical induced contractions by acetylcholine antagonists atropine ), acetylcholine release blocking agents (morphine, tetrodotoxin, procaine , noradrenaline) and prostaglandin synthesis inhibitors (indomethacin, ibuprofen, flufenamine acid, hydrocortisone).
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
Atropine (10(-6) M) shifted the concentration-response curve of cocaine, but not those of lidocaine and procaine , rightward, with a pA2 value (7.66) similar to that obtained with carbachol (7.99).
The American journal of physiology  •  1996  |  View Paper
In contrast, acetylcholine excites smooth muscle directly since procaine , cocaine, and hexamethonium do not affect contractions but atropine inhibits them.
Life sciences  •  1967  |  View Paper