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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Atropine
supplement:
Phosphatidylinositol 4,5-Diphosphate
Research Papers that Mention the Interaction
“ Atropine (10 microM) completely inhibited both DAG accumulation and the breakdown of phosphatidylinositol 4-monophosphate and 4,5-bisphosphate (PIP2) 5 min after stimulation with CCh.”
“In contrast, the breakdown of PIP2 at 20 min was completely inhibited by 10 microM atropine , but DAG accumulation was not.”
A protein kinase C-dependent mechanism(s) is involved in atropine-resistant accumulation of diacylglycerol in rat parotid gland.“Phospholipase C‐dependent hydrolysis of phosphatidylinositol 4,5‐bisphosphate was significantly enhanced by ANTT and atropine , but not by dyflos.”
“Addition of carbamylcholine to 32P‐prelabeled dissociated avian salt gland cells resulted in increased turnover of phosphatidic acid, phosphatidylinositol, phosphatidylinositol 4‐phosphate and phosphatidylinositol 4,5‐bisphosphate , which could be prevented by the inclusion of atropine.”
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