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“ Atenolol (4 x 10(-8) M) exposure of the right ventricle strip intensified the negative inotropic effect of cocaine (3.0-10 micrograms/ml) seen by ventricle stimulation at 210 and 310 systoles/min.”
“The myocardial direct depressant effect of cocaine , in the presence of atenolol , was gradually reversed by extracelular Ca2+ increase at 3.2 and 5.0 mM, respectively.”
“Propranolol, atenolol , and labetalol all antagonized the tachycardiac effect of cocaine in a dose-dependent manner, while the beta-2 antagonist ICI 118,551 did not.”