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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Asymmetric Dimethylarginine and Tetrahydrobiopterin

Research Papers that Mention the Interaction

For …, ADMA promotes eNOS uncoupling, which, through a vicious … of reactive oxygen species (ROS) formation, tetrahydrobiopterin oxidation , and peroxynitrite formation, leads to overt endothelial dysfunction and an impaired vascular regenerative capacity.2 Moreover, it has been observed that ADMA has prooxidative and proinflammatory effects in cells lacking NO formation.
Circulation research  •  2010  |  View Paper