supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Asymmetric Dimethylarginine
drug:
Methacholine
Research Papers that Mention the Interaction
“Exogenous administration of ADMA to naive mice, at doses consistent with the levels observed in the allergically inflamed lungs, resulted in augmentation of the airways responsiveness to methacholine.”
Asymmetric dimethylarginine is increased in asthma.“Exogenous administration of ADMA has been shown to augment airway responsiveness to methacholine in murine models of asthma and increased ADMA levels were observed in lung homogenates and sputum specimens from humans with asthma [2].”
“ ADMA infusion resulted in significantly enhanced lung resistance and decreased dynamic compliance in response to methacholine.”
Elevated asymmetric dimethylarginine alters lung function and induces collagen deposition in mice.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback