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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Asymmetric Dimethylarginine and Methacholine

Research Papers that Mention the Interaction

Exogenous administration of ADMA to naive mice, at doses consistent with the levels observed in the allergically inflamed lungs, resulted in augmentation of the airways responsiveness to methacholine.
American journal of respiratory and critical care medicine  •  2011  |  View Paper
Exogenous administration of ADMA has been shown to augment airway responsiveness to methacholine in murine models of asthma and increased ADMA levels were observed in lung homogenates and sputum specimens from humans with asthma [2].
European Respiratory Journal  •  2013  |  View Paper
ADMA infusion resulted in significantly enhanced lung resistance and decreased dynamic compliance in response to methacholine.
American journal of respiratory cell and molecular biology  •  2009  |  View Paper