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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Asymmetric Dimethylarginine and Atorvastatin

Research Papers that Mention the Interaction

Atorvastatin significantly lowered total cholesterol, LDL cholesterol, and ADMA after 1 day of treatment, while triglycerides, ApoB and hsCRP were lowered after 3 months.
Scandinavian cardiovascular journal : SCJ  •  2008  |  View Paper
Both rosuvastatin and atorvastatin decreased plasma ADMA levels; rosuvastatin had a significantly greater effect.
Angiology  •  2014  |  View Paper
ADMA concentration of cardiac tissues was also significantly reduced in the high-dose atorvastatin group.
ConclusionIn rats with dyslipidemia, atorvastatin therapy could reduce plasma level of ADMA and ADMA concentration in cardiac tissues, and these effects are associated with the dose of atorvastatin therapy.
Lipids in Health and Disease  •  2015  |  View Paper
Nevertheless, in comparison to control group, NO production was profoundly increased and serum levels of MDA, CRP and ADMA were significantly decreased with atorvastatin or rosiglitazone therapy.
Lipids in Health and Disease  •  2014  |  View Paper
Insulin-resistant rats exhibited not only decreases in the DDAH activity and aortic expression of DDAH1 and sterol regulatory element-binding protein 1 (SREBP1) but also increases in plasma ADMA levels, all of which were inhibited by atorvastatin.
Vascular medicine  •  2012  |  View Paper
Atorvastatin administration significantly reduced the ADMA levels without affecting the levels of plasma lipids.
Brain Research  •  2007  |  View Paper