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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Asymmetric Dimethylarginine
drug:
Aliskiren
Research Papers that Mention the Interaction
“CR increased plasma ADMA levels, which aliskiren prevented.”
“We tested whether aliskiren treatment in early postnatal life can reduce ADMA and regulate the renin-angiotensin system to prevent hypertension in rat offspring exposed to maternal caloric restriction (CR).”
Aliskiren in early postnatal life prevents hypertension and reduces asymmetric dimethylarginine in offspring exposed to maternal caloric restriction“ Aliskiren mitigated the increases in plasma ADMA in SHRs.”
“Early aliskiren treatment mitigates increases in ADMA , restores l-Arg-to-ADMA ratios, enhances neuronal NOS-α, prevents decreased nNOS-β levels in the kidney-which might restore NO bioavailability and contribute to the decrease of blood pressure in young SHRs.”
“ Renal ADMA levels were lower in SHRs that received high-dose aliskiren versus SHRs.”
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