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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Astaxanthin
drug:
Rosiglitazone
Research Papers that Mention the Interaction
“ ASX alone did not stimulate 3T3-L1 cell differentiation, although it antagonized 3T3-L1 cell differentiation and lipid accumulation induced by RGZ , similar to the PPARγ antagonist GW9662.”
“However, ASX was unable to activate transcription in PPARγ reporter assays, although it antagonized transcriptional activation by the PPARγ agonist rosiglitazone (RGZ).”
“In addition, ASX effectively blocked the increase in CBP recruitment to PPARγ mediated by RGZ.”
Astaxanthin functions differently as a selective peroxisome proliferator-activated receptor γ modulator in adipocytes and macrophages.
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