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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Aspirin
supplement:
Panax Notoginseng
Research Papers that Mention the Interaction
“ PNS and its main constituents Rg1 and Rd directly inhibited platelet aggregation of healthy subjects with VerifyNow Aspirin and P2Y12 assays but less affecting on coagulation compared with dual-antiplatelet (DAPT).”
Cardioprotection of Panax Notoginseng saponins against acute myocardial infarction and heart failure through inducing autophagy.“ Aspirin and salicylic acid could destroy the tight junction protein and open the intercellular space to increase the absorption of Panax notoginseng saponins.”
Effect of aspirin on the pharmacokinetics and absorption of panax notoginseng saponins.“The results suggested that drug-drug interaction in vivo existed between PNS and ASA.”
“This result suggested PNS could increase the gastrointestinal tract absorption of ASA and SA.”
“The combination of PTS and aspirin could reduce adverse gastrointestinal effects by regulating the TXA 2 /PGI 2 ratio.”
Anti-platelet aggregation of Panax notoginseng triol saponins by regulating GP1BA for ischemic stroke therapy“Our previous studies have already showed that PNS could reduce the gastrointestinal mucosal injury caused by aspirin in preclinical study.”
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