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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aspirin
supplement:
Masoprocol
Research Papers that Mention the Interaction
“The biosynthesis of the 11- and 12-hydroxy products was calcium dependent, localized to the 100,000×g supernatant cell fraction, and was inhibited by nordihydroguaiaretic acid , but not inhibited by the prostaglandin synthase inhibitors aspirin and indomethacin, or the monoxygenase inhibitor proadifen.”
Discovery of an 11(R)- and 12(S)-lipoxygenase activity in ovaries of the mussel Mytilus edulis“Furthermore, combined treatment of aspirin and NDGA almost abolished the increase of alpha-naphthol-induced covalent binding, suggesting that PHS and LPO are both major pathways for xenobiotic activation in platelets.”
“When NDGA was added to mixed cultures of splenocytes and macrophages containing low dose aspirin , it decreased the IL-3 production.”
“However, when aspirin was given in combination with NDGA , phenidone or FPL‐55712, the peak and the following prolonged bronchoconstriction were significantly inhibited.”
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