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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Aspirin and Iron, Dietary

drug:

Aspirin

supplement:

Iron, Dietary

Research Papers that Mention the Interaction

An increasing biologically plausible possibility [2, 3] is that prolonged use of aspirin protects by causing progressive depletion of stored iron.
Annals of Internal Medicine  •  1995  |  View Paper
Acetylsalicylic acid induced an increase in cholesterol, triglyceride, and iron ; albumin, uric acid, and creatinine decreased with ibuprofen therapy.
Clinical chemistry  •  1985  |  View Paper
In agreement with this, cytotoxicity induced by iron , the main catalyst of oxygen radical formation, was substantially reduced by aspirin but not vitamin E. These results show that aspirin protects endothelial cells from oxidative stress possibly via binding or chelation of free cytosolic iron.
FEBS letters  •  1997  |  View Paper
Conductivity titration curves of Fe(OH)3 added to water or ASA suggested that the ASA was complexing with iron.
The Journal of clinical investigation  •  1988  |  View Paper