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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Aspirin and Docosahexaenoic Acid

Research Papers that Mention the Interaction

This finding suggests that … metabolic transformation of DHA incorporated in colon cells … the presence of ASA could, at least in part, explain the colon cancer preventive activity of this drug, and it might … for a synergistic effect of ASA and ω-3 PUFA in the prevention of colon cancer.
BioMed research international  •  2015  |  View Paper
ASA blocks the enzyme cyclo-oxygenase-2 and thus decreases the formation proinflammatory eicosanoids, and as a result, the cellular content of precursor PUFAs (such as AA, EPA, and DHA ), which have antibacterial actions, is increased.
In this context, it is noteworthy that ASA enhances the formation of LXA4, resolvins, and protectins from their respective precursors AA, EPA, and DHA (19).
Critical care medicine  •  2016  |  View Paper