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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aspirin
supplement:
Asymmetric Dimethylarginine
Research Papers that Mention the Interaction
“Statins, renin-angiotensin-aldosterone system inhibitors, blood glucose lowering agents, insulin sensitizers, beta-blockers, estrogen replacement therapy, antioxidants, complex B vitamins, L-arginine and acetylsalicylic acid have been evaluated for their ability to reduce ADMA levels or inhibit its actions.”
Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches.“Furthermore, aspirin reduced the elaboration of asymmetric dimethylarginine ( ADMA), an endogenous inhibitor of NO synthase, and up-regulated the activity of dimethylarginine dimethylaminohydrolase, the enzyme that degrades ADMA.”
“ Aspirin at the dose of 30 mg/kg, but not at higher dose (100 mg/kg), significantly reduced the concentration of ADMA and increased the activity of DDAH.”
Aspirin protected against endothelial damage induced by LDL: role of endogenous NO synthase inhibitors in rats.
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