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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Aspartic Acid and Valproic Acid

Research Papers that Mention the Interaction

At the same time, administration of valproic acid induced a decrease of aspartic acid in the CSF of epileptics.
Acta neurologica Scandinavica  •  1988  |  View Paper
DPAT or 5-HT injections decreased the duration of electrographically-determined waking, increased the durations of D and induced the emergence of SWS and REMS states indistinguishable from the hippocampal EEG associated with spontaneous sleep, as judged from visual and spectral analysis.
Behavioural Brain Research  •  2013  |  View Paper
We have previously reported that chronic administration of valproate in developing mice decreased brain aspartic and glutamic acid levels and increased the brain taurine content.
Life sciences  •  1989  |  View Paper
When D ,L-carnitine was added with VPA to the medium, the level of ammonia decreased significantly and that of ketone bodies increased.
Biochemical pharmacology  •  1988  |  View Paper
Valproic acid acutely alters regional brain concentrations of GABA and of aspartic and glutamic acids in vivo, and it potentiates the action of these amino acid neurotransmitters on neurons in vitro.
Neurology  •  1985  |  View Paper