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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Aspartic Acid and Tryptophan

supplement:

Aspartic Acid

supplement:

Tryptophan

Research Papers that Mention the Interaction

In particular, the substitution of Trp for the hydrophobic amino acids, Gln and Asp at positions 17 and 19 of HP (2-20) (Anal 3), caused a dramatic increase in antibiotic activity without a hemolytic effect.
Biochimica et biophysica acta  •  2002  |  View Paper
on administering to them of D, L-tryptophan in a load dose the infants started vomiting.
Voprosy pitaniia  •  1976  |  View Paper
Although L-tryptophan inhibited the actions of cholecystokinin, L-phenylalanine, L-methionine or L-aspartic acid , even when tested at concentrations as high as 3 mM, did not alter the action of cholecystokinin on pancreatic acini.
Biochimica et biophysica acta  •  1983  |  View Paper
In the closed state, four tightly packed transmembrane helices define a narrow channel, in which a tryptophan gate’ is locked by intermolecular interactions with aspartic acid.
Nature  •  2008  |  View Paper
Charged and polar residues D , H, K, N, Q, R, S) are more incident in the immediate surrounding of tryptophan (-6, -5, -2, -1, 1, 2, 4) and hydrophobic residues (A, F, I, L, V, Y) are more rare than in remote positions.
Molekuliarnaia genetika, mikrobiologiia i virusologiia  •  2001  |  View Paper