supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Aspartic Acid
supplement:
Tryptophan
Research Papers that Mention the Interaction
“In particular, the substitution of Trp for the hydrophobic amino acids, Gln and Asp at positions 17 and 19 of HP (2-20) (Anal 3), caused a dramatic increase in antibiotic activity without a hemolytic effect.”
Design of novel analogue peptides with potent antibiotic activity based on the antimicrobial peptide, HP (2-20), derived from N-terminus of Helicobacter pylori ribosomal protein L1.“on administering to them of D, L-tryptophan in a load dose the infants started vomiting.”
“Although L-tryptophan inhibited the actions of cholecystokinin, L-phenylalanine, L-methionine or L-aspartic acid , even when tested at concentrations as high as 3 mM, did not alter the action of cholecystokinin on pancreatic acini.”
Structure-function studies of N-acyl derivatives of tryptophan that function as specific cholecystokinin receptor antagonists.“In the closed state, four tightly packed transmembrane helices define a narrow channel, in which a tryptophan gate’ is locked by intermolecular interactions with aspartic acid.”
Structure and mechanism of the M2 proton channel of influenza A virus“Charged and polar residues D , H, K, N, Q, R, S) are more incident in the immediate surrounding of tryptophan (-6, -5, -2, -1, 1, 2, 4) and hydrophobic residues (A, F, I, L, V, Y) are more rare than in remote positions.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback