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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Aspartic Acid
drug:
Tobramycin
Research Papers that Mention the Interaction
“Although Mg (2+) and tobramycin are relatively simple ligands, both modulate tRNA ( Asp ) folding in unanticipatedly complex ways, neither of which is consistent with simple hierarchical folding or unfolding of this RNA.”
“The tobramycin polycation binds to loops in tRNA ( Asp ) and induces RNA unfolding in two distinct transitions: the loss of tertiary interactions between the T- and D-loops followed by complete unfolding of the D-stem.”
Complex ligand-induced conformational changes in tRNA(Asp) revealed by single-nucleotide resolution SHAPE chemistry.
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