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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Aspartic Acid
drug:
Steroids
Research Papers that Mention the Interaction
“The catalytic efficiencies for steroid oxidation were reduced 4-10-fold for the Asp 50 mutants and 300-fold for the H117A mutant.”
Mutagenesis of 3 alpha-hydroxysteroid dehydrogenase reveals a "push-pull" mechanism for proton transfer in aldo-keto reductases.“Recently, Park et al. [… that the substitution of aspartic acid to nonaspartic acid at codon 57 of DQb1 showed … association with relapse of autoimmune pancreatitis (AIP) treated with steroid (nonrelapse group, 29.6%; relapse group, 100%; P = 0.00003; … ratio, 3.38; 95% confidence interval, 1.9–6.0).”
“Increased intraocular pressure due to the postoperative steroid medication (dexamethasone 0.1% or prednisolone 1%) was manifest in about 30% in patients with a baseline myopia of up to -9.0 D. In myopia over -9.0 D the incidence of steroid glaucoma was about 50%.”
“Actinomycin D Act D ) added simultaneously with, or slightly prior to, the steroid prevents the suppressive action on cells from adrenalectomized animals but not on cells from intact animals.”
Corticosterone suppression of ACTH secretion: actinomycin D sensitive and insensitive components of the response.“Pts on D also received steroid prophylaxis.”
A prospective evaluation of quality of life (QOL) in a phase II trial of pemetrexed (P) plus carboplatin (Cb) ± enzastaurin (E) versus docetaxel (D) plus Cb as first-line treatment of patients (pts) with advanced non-small cell lung cancer (NSCLC).“Pts on D also received steroid prophylaxis.”
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