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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Aspartic Acid
drug:
Spermine
Research Papers that Mention the Interaction
“The depression of responses to NMDA by spermine was highly voltage dependent (z delta = 1.17) with an apparent equilibrium dissociation constant for block at 0 mV of 27 mM. 3.”
Multiple effects of spermine on N‐methyl‐D‐aspartic acid receptor responses of rat cultured hippocampal neurones.“ Spermine affects the resonances of the D and anticodon stems, and A23G9, but does not stabilize them.”
“Regardless of 5S rRNA assembly status, binding of spermine induced significant changes in the 5S rRNA conformation; loop A adopted an apparent ‘loosening’ of its structure, while loops C, D , E and helices III and V achieved a more compact folding.”
Changes in the conformation of 5S rRNA cause alterations in principal functions of the ribosomal nanomachine
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