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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Aspartic Acid
drug:
Potassium Chloride
Research Papers that Mention the Interaction
“Na(+)/K(+)-dependent interconversion of the oligomers was analysed using HPLC at 0 degrees C. With increasing KCl concentrations, the content or amount of D increased from 27.6 to 54.3% of total protein, i.e. DeltaC(max) = 26.7%.”
“After constant basal levels of amino acid release were obtained, exposure to a depolarizing concentration of KCl (30 mM) evoked 4.05-, 2.18- and 3.00-fold increases in release of glutamic acid (Glu), aspartic acid (Asp) and gamma-aminobutyric acid (GABA) from synaptosomes.”
“At 35 degrees C and in the presence of 10 mM KCl , the pKa values for Asp 7, Glu 19, and Asp 27 (< 2.6, 3.2, and < 2.3, respectively) are more than 1 pH unit below those for model compounds.”
“Exposure to a depolarizing concentration of KCl (30 mM) resulted in 1.7 to 3.6-fold increases in Asp , Glu and GABA release.”
Presynaptic inhibition by clonidine of neurotransmitter amino acid release in various brain regions.“The incorporation of L-aspartic acid was found to decrease the helix content of the polymer at both high and low pH, in water and also in 0.1 N KCl.”
Helix-coil stability constants for the naturally occurring amino acids in water. 16. Aspartic acid parameters from random poly(hydroxybutylglutamine-co-L-aspartic acid).
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