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“Rats treated with Mn exhibited a significant reduction in brain TAS (-39%, P < 0.001, B versus A) that was partially reversed by Cys co-administration (-13%, P < 0.01, D versus A), while Cys (group C) had no effect on TAS.”
“The manganese concentrations in basal ganglia were increased proportionally to the administration dosages in intravenous administration groups (C, D and E).”
Nihon eiseigaku zasshi. Japanese journal of hygiene • 1989 | View Paper
“In contrast manganese produced a strong, voltage‐dependent block of responses to NMDA , similar to that produced by magnesium, such that even close to the reversal potential the NMDA current‐voltage relationship was highly non‐linear.”