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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Aspartic Acid and Leucine


Aspartic Acid



Research Papers that Mention the Interaction

Mutagenesis of aspartic acid at position 382 in the hydrophilic interface to leucine (D382L) reduced the binding and uncoupled the receptor from G protein activation.
The Journal of biological chemistry  •  2006  |  View Paper
However, substitution of either aspartic acid 202 with valine or proline 203 with leucine dramatically inhibited WHV production.
Hepatology  •  1998  |  View Paper
Reduced major axis regression of L with respect to D showed that alpha = 2.82 ± 0.14 for S. thurberi, 2.32 ± 0.19 for L. schottii, and 4.21 ± 0.31 for S. gummosus.
American journal of botany  •  1998  |  View Paper
A 1,000-fold higher concentration of l-leucine (l-Leu) can inhibit all of the energy-dependent uptake of l-Arg, l-Asp , l-His, and l-Phe.
Plant physiology  •  1982  |  View Paper
If at any time D will exceed L by a small number, due to a fluctuation, D will grow exponentially and L will be destroyed.
Journal of Molecular Evolution  •  1975  |  View Paper
Over the 33 to 15 degrees C range the VO(2) values in D exceeded those in L by approximately 30%.
Journal of applied physiology  •  2000  |  View Paper
A switch from D to B revived an insulin response to leucine.
Molecular and Cellular Endocrinology  •  1986  |  View Paper
L-leucine reduced the islet content of aspartic acid whereas D-glucose, when added to L-leucine-incubated islets, increased the contents of aspartic acid and gamma-aminobutyric acid (GABA).
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  1976  |  View Paper