Possible Interaction: Aspartic Acid and Leucine

“When D exceeded 3.9 mm and L exceeded 10.0 mm, the tangent slope rate of the maximum von Mises stress response curve ranged from -1 to 0.”

“There was a positive correlation between D and L in W5 (r = 0.25) and W9 (r = 0.36; P < 0.05).”

“Mutagenesis of aspartic acid at position 382 in the hydrophilic interface to leucine (D382L) reduced the binding and uncoupled the receptor from G protein activation.”

“However, substitution of either aspartic acid 202 with valine or proline 203 with leucine dramatically inhibited WHV production.”

“The fraction of the oral dose appearing in the systemic circulation was variable … EAA in both N and D. Total body clearance was significantly lower in D (P less than 0.…) for theronine, phenylalanine, valine, leucine , and isoleucine, and this difference could not … explained by changes in renal excretion.”

“We found highly significant correlations between the δ15N ratios of leucine to the δ15N ratios of glutamic acid, proline, alanine, tyrosine and aspartic acid at oligotrophic sites of enhanced nitrogen fixation.”

“Over the 33 to 15 degrees C range the VO(2) values in D exceeded those in L by approximately 30%.”

“A switch from D to B revived an insulin response to leucine.”

“ L-leucine reduced the islet content of aspartic acid whereas D-glucose, when added to L-leucine-incubated islets, increased the contents of aspartic acid and gamma-aminobutyric acid (GABA).”

“ L and D promotes short-term antinociceptive effects for up to 15 min and, when used in combination with D , increased the duration and extent of sensory block by up to 45 min.”