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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Aspartic Acid
drug:
Ketamine
Research Papers that Mention the Interaction
“Physostigmine and aspartic acid , but not haloperidol, diminished ketamine amnesia, therefore ketamine impaired the interaction of cholinergic and glutamate/aspartatergic neurons of hippocampal areas.”
Pharmacological correction of ketamine-impaired spatial memory of rats“In the presence of ketamine , peak inward currents evoked by repeated applications of NMDA, L-Asp , or L-Glu progressively declined to a steady-state level of block (use-dependent block).”
“The short-acting dissociative anaesthetic, ketamine (2-50 microM), selectively blocked L-aspartic acid (L-Asp), NMDA, and L-glutamic acid (L-Glu) currents while sparing those in response to KAI.”
“The dissociative anesthetics, ketamine and phencyclidine caused a selective depression in the change in conductance evoked by L-ASP but not that by KA.”
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