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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Aspartic Acid and Insulin


Aspartic Acid



Research Papers that Mention the Interaction

Both K and D correlated well with the charge properties of the insulin and membrane: when the insulin and membrane carried opposite net charge, the partition coefficient showed relatively larger values, while the effective diffusion coefficient was reduced.
Biotechnology progress  •  2009  |  View Paper
Cells preincubated with microfilament … A, B, and D (10 mug/ml), … binding of insulin (30%) and human growth hormone (60%) under steady state conditions, which was not reversed by removing the cytochalasins … the medium and was due entirely to a reduced number of receptor sites on the cell surfact.
The Journal of biological chemistry  •  1976  |  View Paper
Various solution additives affect the solubility and macroaggregation of insulin in buffered aqueous solutions at physiological pH. The solubility of insulin may be improved with the addition of small amounts of aspartic acid , glutamic acid, EDTA (ethylenediaminetetraacetic acid), lysine, Tris buffer, or bicarbonate buffer.
Journal of pharmaceutical sciences  •  1983  |  View Paper
The effects of insulin were prevented by 15 min pretreatment with 2 micrograms ml-1 cycloheximide or by 2 micrograms ml-1 actinomycin D , suggesting a role for new protein synthesis in the actions of insulin on glucose transport in this cell type.
Experimental eye research  •  1986  |  View Paper