supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Aspartic Acid
drug:
Indomethacin
Research Papers that Mention the Interaction
“ Indomethacin infusion completely prevented both the antiischemic activity of D and its ability to increase the generation of prostaglandins in the rabbit heart.”
Defibrotide has antiischemic activity in perfused rabbit hearts, preventing tissue Ca++ overloading.“ IND augmented the AII response and prevented the effect of D , suggesting the renal vasodilator effect of D is, at least in part, PGI2-mediated.”
“The magnitude … by indomethacin was greater in treatment A than in treatment B. The difference in the magnitude of the inhibition between treatment C and D … concentration of indomethacin, however, at a lower concentration (0.01 mM) the percent inhibition was 3 and 42 for treatments C and D, ….”
“ Indomethacin (10-5 M) increased both D max and D min and completely inhibited AA-induced constrictions, but did not affect PGE2-induced dilations of lymph microvessels.”
Regulation of the vasomotor activity of lymph microvessels by nitric oxide and prostaglandins.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback