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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Aspartic Acid
supplement:
Histidine
Research Papers that Mention the Interaction
“This together with a 1H chemical shift of 19.93 ppm is evidence that the hydrogen bond distance between His and Asp is shorter than for SIHB.”
Direct evidence of a low barrier hydrogen bond in the catalytic triad of a Serine protease“Substitution of a histidine for aspartic acid at alpha 47 causes a marked inhibition of polymerization.”
“The substitution of histidine with citruline, aspartic acid , norleucine or diaminobutyric acid in position 14 of the amino acid chain led to a considerable increase in potency, suggesting that amino acids located at this position might play a crucial role where the strength of short analogues is concerned.”
Increased potency of some substituted short peptide analogues in comparison to galanin(1-15)-NH(2)in rat fundus strips.“ACMN prefers to adsorb Asp over His in the competitive sorption of coexisting Asp and His because of attractive electrostatic interactions.”
Effects of pre-oxidation and adsorption on haloacetonitrile and trichloronitromethane formation during subsequent chlorination“Although the Asp residue in this motif is known to substantially increase the basicity of the His residue, no proton transfer from His 131 to Asp 166 was observed on binding of TSA or water.”
“Moreover, all mutants could not maintain the nucleosome-like structure (compacted form of DNA) above 80 degrees C. These results suggest that surface ion pairs between His and Asp play an important role in maintenance of nucleosome structure and DNA stabilization at high temperature.”
“Electron density is observed for an unusual, short hydrogen bond between aspartic acid and histidine in the catalytic triad.”
“In this study, we found little or no effect of histidine residues preceding an asparagine residue in hexapeptides derived from the sequence of adrenocorticotropic hormone, while a histidine residue preceding an aspartic acid residue was found to increase the rate of succinimide formation 8- to 11-fold.”
“The other mutation, hisG3935, allows the histidine operon to be partially repressed by several amino acids, including aspartic acid.”
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