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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Aspartic Acid
drug:
Dopamine
Research Papers that Mention the Interaction
“Asn351 to Asp resulted in an approximately 10-fold decrease in dopamine and threefold decrease in R(+)-SKF-38393 binding affinities.”
Functional analysis of the human D5 dopamine receptor missense and nonsense variants: differences in dopamine binding affinities.“5 We report herein, using human tissues, that the density of D 2 is underestimated by radioactive raclopride in the presence of dopamine.”
“In the absence of Mg2+, 20 µM NMDA caused a transient “release” of dopamine and decreased the background signal.”
Real‐Time Effects of N‐Methyl‐d‐Aspartic Acid on Dopamine Release in Slices of Rat Caudate Putamen: A Study Using Fast Cyclic Voltammetry“In the presence of magnesium, L-glutamate, D ,L-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-4-propionate (AMPA) and kainate, but not N-methyl-D-aspartate (NMDA) and 1-aminocyclopentane-1S,3R-dicarboxylate (t-ACPD), stimulated the release of [3H]dopamine , in a dose-dependent manner.”
“Nemonapride, D ,L-sulpiride, and remoxipride significantly reduced the number of spontaneously active dopamine neurones in the ventral tegmental area, indicating an antipsychotic potential, while raclopride and zacopride induced but minor effects.”
“ Dopamine (DA) almost completely inhibited the K(+)-evoked release of Asp and Glu in a concentration-dependent manner, but the release of GABA was only partly inhibited.”
“The dopamine release evoked by burst stimulation (20 s with a mean frequency of 6 Hz) was dose-dependently decreased by D ,L-apomorphine (25-800 micrograms/kg, s.c.)”
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