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Last Updated: 2 years ago

Possible Interaction: Aspartic Acid and Clonidine

supplement:

Aspartic Acid

Research Papers that Mention the Interaction

When leukocytes were incubated simultaneously with D 4026 and a histamine H-2 receptorstimulating drug (histamine or clonidine ), the two drugs combined induced an inhibition significantly greater than the sum of their individual inhibitory effects.
Agents and Actions  •  2005  |  View Paper
When clonidine (10(-4) M) was added to the perfusion medium, the K(+)-evoked overflow of both Asp and Glu was inhibited by 50-90% in the anterior cortex, thalamus and hypothalamus.
European journal of pharmacology  •  1992  |  View Paper
Clonidine inhibited K(+)-evoked Glu and Asp overflow to 40 and 30% of the control with a potency (IC50) of 11 and 36 nM, respectively.
Clonidine inhibited the K(+)-evoked overflow of Glu and Asp in a concentration-dependent manner, but the GABA overflow was not inhibited.
Brain Research  •  1991  |  View Paper
D inhibited the contraction evoked by KC1 40 mmol/L in rabbit … IC50 value of 93 Umol/L. The dase-response curve for clonidine to inhibit electrical stimulation-evoked contraction of the … rat vas deferens was shifted rightward parallejly by D 30, 100 vmol/L … value of 5.1.
Zhongguo yao li xue bao = Acta pharmacologica Sinica  •  1988  |  View Paper