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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Aspartic Acid
drug:
Aspartate
Research Papers that Mention the Interaction
“Peptides with one aspartic acid have a higher intrinsic Ca2+ affinity than those with two aspartates.”
Intrinsic Ca2+ affinities of peptides: Application of the kinetic method to analogs of calcium-binding site III of rabbit skeletal troponin C“ NMDLA , which has no activity as an agonist, was a greater suppressant of the responses to L‐aspartate than those to L‐glutamate.”
“The Na‐dependent binding of L‐[3H]‐aspartate ( Kd= 484 nM) was strongly inhibited by D‐aspartate, L‐glutamate, D ,L‐aspartate β‐hydroxamate; was unaffected by calcium and magnesium; and showed a different pattern of distribution: cerebral cortex > cerebellum = pons‐medulla = spinal cord.”
“The D and L forms of the dipeptide, gamma-glutamylglycine depress NMDA-, L-aspartate- and kainate-induced excitation in cat spinal cord while little or nor effect on L-glutamate- and quisqualate-induced responses.”
“After a conditioning dose of D or l‐glutamate, responses to d or L‐aspartate were enhanced.”
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