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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aspartate
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“Both Mg chloride and Mg L-aspartate in combination with vitamin B6 caused statistically significant compensation of magnesium deficit.”
[Comparative study of magnesium salts bioavailability in rats fed a magnesium-deficient diet].“It was shown in our study that administration of Mg L-aspartate with pyridoxine leads to higher compensation of Mg deficiency in rats with diet-induced Mg depletion as compared with other Mg supplementations.”
“Preincubation of nervous tissue with pyridoxal-5'-phosphate (40 microM) results in significant acceleration of catabolism of [1-14C] alpha-ketoglutarate, [5-14C] alpha-ketoglutarate and [4-14C] aspartate with an inconsiderable increase of catabolism of the rest of labelled substrates.”
“When aspartate- and alanine transaminase (AST and ALT, respectively) activities were studied in homogenates of rat cerebellum, brain cortex and brain stem (using a modified procedure by Raitman and Frenkel), addition of 50 microM pyridoxal-5-phosphate ( PALP ) increased 2-3-fold the activity studied.”
“Absorption and tissue pooling were found to be augmented when using the aspartate and even more when adding vitamin B6.”
“As shown in Table 1, aspartate transaminase activity was decreased in the pyridoxine deficient group to 42% of the normal group.”
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