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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Aspartame and Glutathione



Research Papers that Mention the Interaction

Chronic … aspartame increased plasma alanine aminotransferase (ALT) and aspartate aminotransferase activities and caused … injury as well as marked decreased hepatic levels of reduced glutathione ( GSH ), oxidized glutathione (GSSG), γ-glutamylcysteine ​​(γ-GC), and most metabolites of the …-sulphuration pathway, such as cysteine, S-adenosylmethionine (SAM), and S-adenosylhomocysteine ​​(SAH).
Redox biology  •  2017  |  View Paper
The administration of only aspartame (22.5 and 45 mg/kg) increased brain TBARS by 17.7–32.8%, decreased GSH by 25.6–31.6%, and increased TNF-α by 16.7–44%.
Neurotoxicity Research  •  2011  |  View Paper