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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Asparagine and Threonine

supplement:

Asparagine

supplement:

Threonine

Research Papers that Mention the Interaction

Replacement of threonine with asparagine decreases the activity of carbamoyl phosphate synthase in the urea cycle.
Anesthesia and analgesia  •  2011  |  View Paper
Substitution of Thr with Asn in the TAA motif of FgAQP-1 increased its water permeability twofold but did not affect urea and glycerol impermeability while the substitution at the pore mouth of Cys204 by Tyr caused loss of water permeability.
Molecular and biochemical parasitology  •  2011  |  View Paper
Both the distance between Thr and Asn and the ordering of the two residues are crucial for effective ice binding.
Biophysical journal  •  1997  |  View Paper
Substitution of Cys at position 39 blocks glycosylation, whereas substitution of Thr dramatically increases core glycosylation efficiency of Asn in both membrane-anchored and secreted forms of RGP.
The Journal of Biological Chemistry  •  1995  |  View Paper
Site-directed mutagenesis experiments showed that replacement of Asn by Thr decreased both the catalytic efficiency and the binding affinity by 2.3- and 7.0-fold, respectively, and substitution of Leu73 for Ala predominantly decreased the binding affinity by 14.
Biochemical and biophysical research communications  •  2000  |  View Paper
Replacement of Asn by residues with shorter side chains resulted in either a small loss (Ala) or gain ( Thr ) of antifreeze activity.
Biochemistry  •  1999  |  View Paper
All other amino acids with the exception of histidine, arginine, asparagine , and hydroxyproline inhibited threonine uptake.
Plant physiology  •  1979  |  View Paper