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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Asparagine and NADH

supplement:

Asparagine

supplement:

NADH

Research Papers that Mention the Interaction

Substitutions of Glu-267 with histidine or asparagine residues increase the dissociation constants for the coenzymes (NAD+ by ∼40-fold, NADH by ∼200-fold) and significantly decrease catalytic efficiencies by 16-1200-fold various substrates and substituted enzymes.
Archives of biochemistry and biophysics  •  2018  |  View Paper
Saturation mutagenesis at position 439 showed that the presence of an asparagine or a phenylalanine improves the catalytic efficiency with NADH by a factor of 6 to 7.
European journal of biochemistry  •  2004  |  View Paper
Asparagine plus NADH shows a synergistic effect in stimulating the incorporation of 3KDS into CPE and CPG in washed cells.
Journal of bacteriology  •  1977  |  View Paper