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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Asparagine and NAD





Research Papers that Mention the Interaction

Substitutions of Glu-267 with histidine or asparagine residues increase the dissociation constants for the coenzymes ( NAD+ by ∼40-fold, NADH by ∼200-fold) and significantly decrease catalytic efficiencies by 16-1200-fold various substrates and substituted enzymes.
Archives of biochemistry and biophysics  •  2018  |  View Paper
The asparagine mutant was approximately 50-fold-attenuated in NAD glycohydrolase activity, however.
Biochemistry  •  1994  |  View Paper