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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Asparagine
supplement:
Methionine
Research Papers that Mention the Interaction
“Metabolomics investigation showed that methionine administration increased 2-hydroxypyridine, salicin, and asparagine and reduced D-Talose, maltose, aminoisobutyric acid, and inosine 5'-monophosphate in the liver, which are widely reported to involve in oxidative stress, lipid metabolism, and nucleotides generation.”
Antioxidant Function and Metabolomics Study in Mice after Dietary Supplementation with Methionine“Our findings indicate that methionine can increase ruminal asparagine content and the population of Compylobactor.”
Effect of Methionine Supplementation on Rumen Microbiota, Fermentation, and Amino Acid Metabolism in In Vitro Cultures Containing Nitrate“Strikingly, the substitution … Tyr278 with methionine impaired the interaction with d-asparagine via water molecules due to the small hydrophobic side chain of methionine, which forced the ligand to the deep side of the active site toward the catalytic residues and thus resulted in the loss of hydrolyzing function.”
“Mutant strains grow poorly at high temperature on minimal plates containing asparagine as the sole nitrogen source; this effect is greatly exacerbated by the presence of methionine.”
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