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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Asparaginase
supplement:
Leucine
Research Papers that Mention the Interaction
“ L-leucine , L-arginine and theophylline also potentiated glucose-induced insulin release in the presence of L-asparaginase.”
E. coli L-asparaginase and insulin release in vitro.“Substitution of Asp-11 by Ser, Arg-13 by Leu , or Trp-26 by Ile decreased enzyme activity to below detectable levels (less than 1.0% of that of the recombinant S-1 subunit).”
ADP-ribosyltransferase mutations in the catalytic S-1 subunit of pertussis toxin“ LAsparaginase inhibited incorporation of fucose and glucosamine into L5 178Y glycoproteins as rapidly as did cycloheximide, but inhibited incorporation of leucine into proteins less rapidly than cycloheximide.”
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