Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)

Try: Ginkgo, Methotrexate, Glucosamine

Last Updated: 3 years ago

Possible Interaction: Asparaginase and Glutathione

Share:

drug:

Asparaginase

supplement:

Glutathione

Research Papers that Mention the Interaction

“Monovalent cations (Na(+) and K(+)) and reducing agents (2-mercaptoethanol and glutathione ) has enhanced asparaginase activity.”

Purification and characterization of glutaminase free asparaginase from Pseudomonas otitidis: Induce apoptosis in human leukemia MOLT-4 cells.

Biochimie • 2016 | View Paper

“Decoy oligonucleotides (ODN) studies further demonstrate that AP-1, SP-1 , and Smad ODNs abrogate the inhibitory effect of GSH on TGF-beta-induced PAI-1 promoter activity and inhibit TGF-beta-induced expression of endogenous PAI-1.”

Glutathione suppresses TGF-beta-induced PAI-1 expression by inhibiting p38 and JNK MAPK and the binding of AP-1, SP-1, and Smad to the PAI-1 promoter.

American journal of physiology. Lung cellular and molecular physiology • 2007 | View Paper

Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback