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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Asparaginase
supplement:
Genistein
Research Papers that Mention the Interaction
“Furthermore, the combined treatments GEN and Asp ) showed a higher decrease in the level of ΔΨm than that of GEN or Asp treatment only.”
“ GEN combined with Asp revealed a more significant decrease in total viable cells and induced a higher percentage of G2/M phase arrest, DNA damage, and cell apoptosis than that of GEN or Asp treatment only in HL-60 cells.”
“ GEN combined with Asp revealed a more significant decrease in total viable cells and induced a higher percentage of G2/M phase arrest, DNA damage, and cell apoptosis than that of GEN or Asp treatment only in HL‐60 cells.”
“ GEN significantly enhances the efficiency of Asp on cytotoxic effects (the induction of apoptosis) in HL-60 cells.”
“ GEN significantly enhances the efficiency of Asp on cytotoxic effects (the induction of apoptosis) in HL‐60 cells.”
“The results from western … that the treatment of GEN combined … Asp showed a higher increase in the levels of Bax and Bak (pro-apoptotic proteins) and an active form of …-3 and a higher decrease in Bcl-2 (anti-apoptotic protein) than that of GEN or Asp treatment alone.”
“The results from western … that the treatment of GEN combined … Asp showed a higher increase in the levels of Bax and Bak (pro‐apoptotic proteins) and an active form of …‐3 and a higher decrease in Bcl‐2 (anti‐apoptotic protein) than that of GEN or Asp treatment alone.”
“These results indicated that GEN combined with Asp induced mitochondria dysfunction by disrupting the mitochondrial membrane potential.”
Genistein enhances the effects of L‐asparaginase on inducing cell apoptosis in human leukemia cancer HL‐60 cells
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