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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Asparaginase and Aspartic Acid

Research Papers that Mention the Interaction

Kinetic studies also revealed that L-aspartic acid inhibited L-asparaginase competitively , with an inhibition constant of 80 microM at micromolar concentrations of L-asparagine; at millimolar concentrations of the amide, an increase in maximal velocity but a decrease in affinity for L-asparagine were observed.
Journal of enzyme inhibition  •  1986  |  View Paper
Asparaginase catalyzed the synthesis of the hydroxamate from asparagine and more slowly from aspartic acid.
The Journal of biological chemistry  •  1971  |  View Paper
The body weight, food and fluid intakes, and rectal temperature of the rats received D-Asp or D + L-Asp in 1/1 ratio significantly decreased.
Polish journal of pharmacology and pharmacy  •  1982  |  View Paper