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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Ascorbate
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“ HS also decreased the rate of reduction by ascorbate of the PtIV complexes relative to the reduction rates in phosphate buffer, suggesting that for this compound class, phosphate buffer is not a good model for HS.”
Probing the Interactions of Cytotoxic [Pt(1S,2S‐DACH)(5,6‐dimethyl‐1,10‐phenanthroline)] and Its PtIV Derivatives with Human Serum“In the presence of biological reducing agent ascorbate, HSA inhibited Cu (II)/Cu (I)-mediated Aβ40 aggregation, reactive oxygen species production, and neurotoxicity.”
“Consequently, complexation to HSA is able to reduce the rate of reduction of the prodrug by ascorbate.”
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