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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ascorbate
drug:
Motexafin Gadolinium
Research Papers that Mention the Interaction
“Incubation with Gd-Tex in the presence of ascorbate increased the aerobic radiation response of E89 and the apoptosis-sensitive B-cell line (LYAS).”
Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species.“Motexafin gadolinium MGd ) oxidizes ascorbate , in neutral buffer and in cell culture, forming reactive oxygen species and a coordination polymer with oxalate.”
Motexafin gadolinium reacts with ascorbate to produce reactive oxygen species.
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