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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Artesunate and Iron, Dietary

supplement:

Iron, Dietary

Research Papers that Mention the Interaction

In conclusion, our results indicate that ferrous iron improves the activity of artesunate in some but not all tumor cell lines.
The susceptibility of tumor cells to artesunate can be enhanced by ferrous iron.
PloS one  •  2007  |  View Paper
Our findings suggest that artesunate acts through iron to affect the mitochondria and induce low ROS and non-caspase–mediated apoptosis.
Oncotarget  •  2014  |  View Paper
It has been demonstrated that Fe could activate the artesunate , leading to the formation of highly reactive carboncentered radicals from AIDs, thus can trigger the alkylation of proteins and generate reactive oxygen species (ROS) to cause cancer cells death.
Signal Transduction and Targeted Therapy  •  2021  |  View Paper