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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Artesunate and Ferrous



Research Papers that Mention the Interaction

Abstract Artesunate (AS), as an effective new tumour treatment drug, induces cancer cell death based on high intracellular reactive oxygen species (ROS) produced by interacting with ferrous ions.
Journal of drug targeting  •  2020  |  View Paper
In conclusion, our results indicate that ferrous iron improves the activity of artesunate in some but not all tumor cell lines.
The susceptibility of tumor cells to artesunate can be enhanced by ferrous iron.
PloS one  •  2007  |  View Paper
Here, we demonstrate that the efficacy of the antiviral effect of ART is augmented by co-treatment of HCMV-infected fibroblasts with ferrous iron , i.e. Ferrosanol, and/or the iron transfer-mediating molecule holo-transferrin.
Antiviral research  •  2006  |  View Paper
As an Fe(II)-dependent drug, the anticancer effect of AS is often limited due to insufficient Fe(II) concentration in targeted cells.
Advanced healthcare materials  •  2019  |  View Paper
Artesunate treatment also reduced biofilm thickness, diffusion in the biomass, and the content of Fe(II).
BioMed research international  •  2019  |  View Paper