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Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban • 2013 | View Paper
“ Artemisinin becomes cytotoxic in the presence of ferrous iron.”
“The endoperoxide bridge, the active moiety of artemisinin derivatives, is cleaved in the presence of ferrous iron , generating reactive oxygen species (ROS) and other free radicals.”