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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Arsenic Trioxide
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Also, arsenic trioxide elevated the intercellular calcium accumulation of H9c2 cell by 2.02-fold v.s control and RTS.”
Realgar transforming solution as a novel arsenic agent with a lower risk of cardiotoxicity.“ As2O3 depleted the calcium store and consequently lead to a decrease of calcium signaling (P = 0.0018).”
“…,ATO markedly increased the resting Ca2+ ratio, amplitude/resting calcium, the maximal velocity of Ca2+ shortening and relaxation (+d[Ca2+]/dtmax and -d[Ca2+]/dtmax), time-to-50% peak [Ca2+] i and the decay rate of [Ca2+] i transients, suggesting that ATO leads to intracellular imbalance of calcium homeostasis.”
Arsenic trioxide triggered calcium homeostasis imbalance and induced endoplasmic reticulum stress-mediated apoptosis in adult rat ventricular myocytes.
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