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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Arginine and Venlafaxine

supplement:

Arginine

Research Papers that Mention the Interaction

Systemic L-arginine (50 mg/kg) pretreatment with sub-effective dose of sertraline (10 mg/kg), venlafaxine (10 mg/kg), imipramine (10 mg/kg) and trazodone (10 mg/kg) for 14 days significantly attenuated their protective effect.
Journal of psychopharmacology  •  2011  |  View Paper
We found in the FST that pretreatment with L-arginine (500 mg/kg) counteracted the antidepressant-like effect of imipramine (IMI, 15 mg/kg) and venlafaxine (VENL, 6 mg/kg), but not the effects of bupropion (BUPR, 20mg/kg) or fluoxetine (FLX, 20mg/kg).
Behavioural Brain Research  •  2011  |  View Paper
L-arginine (50 mg/kg) pretreatment for 14 days together with a subeffective dose of sertraline (10 mg/kg), venlafaxine (10 mg/kg), imipramine (10 mg/kg) or trazodone (10 mg/kg) partially attenuated their protective effects.
Behavioural pharmacology  •  2010  |  View Paper
Further, protective effects of desipramine (15 mg/kg) and/or venlafaxine (5 mg/kg) were attenuated by l-arginine (100 mg/kg) or sildenafil (5 mg/kg) pretreatment.
Brain Research  •  2010  |  View Paper
However, L-arginine (100 mg/kg) pretreatment with venlafaxine (5 mg/kg) significantly reversed the protective effect of venlafaxine (P<0.05).
Brain Research  •  2010  |  View Paper
l-arginine (100mg/kg) pretreatment with imipramine (10mg/kg) and venlafaxine (5mg/kg) significantly attenuated the protective effect of imipramine and venlafaxine.
Neuroscience Letters  •  2009  |  View Paper
However, l-arginine (50mg/kg) pretreatment with venlafaxine (5mg/kg) reversed the protective effect of venlafaxine.
Behavioural Brain Research  •  2008  |  View Paper