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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“The flux of L-arginine through arginase in intact cells was inhibited by 51+/-11% by 10 mM of DFMO whereas 10 mM of L-valine , a known potent arginase inhibitor, inhibited this flux by 73+/-6%.”
Alpha-difluoromethylornithine (DFMO) as a potent arginase activity inhibitor in human colon carcinoma cells.“ L-Valine , a known arginase inhibitor, when used at a high concentration, i.e., 100 mM, inhibits L-arginine flux through arginase almost totally.”
“The addition of the combination L-Arg and L-Val decreased urea production compared with the addition of L-Arg alone and increased NO production compared with L-Val alone.”
Arginase inhibition increases nitric oxide production in bovine pulmonary arterial endothelial cells.“NEM-sensitive arginine transport is inhibited by leucine, phenylalanine, alanine and valine.”
“One-to-one molar ratios of arginine heated with threonine, valine , cystine, cysteine or tryptophan produced reaction products that gave 1200-3200 revertants/mmol in Salmonella strain TA98 with metabolic activation.”
Formation of mutagenic activity from amino acids heated at cooking temperatures.
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