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“It is inhibited by arginine and pyrimidines, and its formation is repressed by uracil , with a concerted effect of arginine at lower uracil concentrations.”
“This enzyme is submitted to a double end-product control: (a) cumulative repression of its synthesis by arginine and uracil ; (b) partial feedback inhibition of its activity by uridine-5′-monophosphate.”
“In this research, an effect of arginine on aspartate transcarbamylase formation was observed only if the bacteria were preincubated with arginine in the presence of uracil analogues that cause apparent partial derepression of this enzyme.”