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Last Updated: 2 years ago

Possible Interaction: Arginine and Trypsin

supplement:

Arginine

supplement:

Trypsin

Research Papers that Mention the Interaction

Trypsin cleaves at substrate arginine and lysine peptides bonds.
Acta cientifica venezolana  •  1991  |  View Paper
Although more than one component of serum has been shown to be capable of hydrolyzing these substrates, it has been suggested that trypsin may be elevated in pancreatic disease and could conceivably account for the enhanced hydrolysis of the arginine substrates.
The New England journal of medicine  •  1966  |  View Paper
Trypsin PC was found to hydrolyze amide bonds formed by carboxylic groups of lysine and arginine in peptide substrates.
Bioorganicheskaia khimiia  •  1998  |  View Paper
Decreased inhibitory activity of the trypsin domain was observed with casein and benzoyl arginine ethyl ester as substrates.
Biochimica et biophysica acta  •  1993  |  View Paper
Pretreatment of the cells with trypsin , which removed Fc epsilon R , markedly diminished the release of IgE-potentiating factor, suggesting that the factor is derived from Fc epsilon R on the cell surface.
Journal of immunology  •  1980  |  View Paper
In the presence of arginine and N-substitute arginines, the elution of trypsin was accelerated.
Journal of biochemistry  •  1976  |  View Paper
The homologues with either lysine or arginine in the P1 position are equally good inhibitors of trypsin , plasmin and kallikrein.
European journal of biochemistry  •  1976  |  View Paper
It was … that trypsin cleaves the C-terminal … lysine (K) and arginine (R) residues with higher rates for R. And the cleavage sites surrounded by neutral residues could be quickly cut, while those with neighboring charged residues (D/E/K/R) or proline residue (P) could be slowly cut.
Analytical and Bioanalytical Chemistry  •  2014  |  View Paper
Modification at lysine and arginine residues, in particular, causes resistance to digestion by trypsin , producing large tryptic peptides that are not readily sequenced by mass spectrometry.
Journal of mass spectrometry : JMS  •  2007  |  View Paper
Trypsin cleaves the peptide bond between the carboxyl group of arginine or the carboxyl group of lysine and the amino group of the adjacent amino acid.
CSH protocols  •  2006  |  View Paper
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